Genzyme has discontinued development of the potential follow-on to its drug Renvela (sevelamer carbonate), as the advanced phosphate binder (APB) did not show a significant improvement in phosphate lowering compared with Renvela in a Phase II/III trial in adult haemodialysis patients with hyperphosphataemia.
Genzyme was seeking to develop a product with higher potency that would more effectively bind phosphate.
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