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Sanofi and Regeneron are trappist with Zaltrap VEGF-Trap data

 
• By Andy Smith

While investors clearly approved of the news from Regeneron and partner Sanofi-Aventis that VEGF-Trap (aflibercept) plus FOLFIRI chemotherapy met the primary endpoint in the Phase III VELOUR clinical trial in patients with second-line metastatic colorectal cancer (mCRC), it is what they did not say that in the release that raises more questions than answers.

While investors clearly approved of the news from Regeneron and partner Sanofi-Aventis that VEGF-Trap (aflibercept) plus FOLFIRI chemotherapy met the primary endpoint in the Phase III VELOUR clinical trial in patients with second-line metastatic colorectal cancer (mCRC), it is what they did not say that in the release that raises more questions than answers.

The hardest endpoint to reach in oncology trials, and the one that the FDA will most likely accept, is a...

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