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Contrave OK'd in obesity; multiple trials required

 
• By Donna Young

Orexigen Therapeutics' and Takeda's anti-obesity drug Contrave (naltrexone SR/bupropion SR) was finally approved by the FDA on 10 September, but not without its many trials and tribulations along the way.

Orexigen Therapeutics' and Takeda's anti-obesity drug Contrave (naltrexone SR/bupropion SR) was finally approved by the FDA on 10 September, but not without its many trials and tribulations along the way.

And with the drug's approval, the FDA has added more trials – of the clinical and nonclinical nature – as postmarketing requirements for the medicine, which is indicated for adults with a body mass index of 30 kg/m2 or greater for obese patients or 27 kg/m2 or greater for those considered overweight in the

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