After a string of failures, Winston-Salem, North Carolina-based Targacept and its neuronal nicotinic receptor (NNR) therapeutics will be replaced by engineered human proteases for hemophilia and complement-mediated disorders in a reverse merger with privately-held Catalyst Biosciences in South San Francisco.
Publicly-held Targacept will be known as Catalyst and its stock market ticker symbol will change from TRGT to CBIO. The combined company will focus entirely on the development of Catalyst's five mostly preclinical therapeutic candidates
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