Eleven Biotherapeutics Inc. more than doubled in value in early trading on June 13 before closing up 27.8% at $2.39 per share after the company said it licensed EBI-031, its lead development program, to Roche – a move that could signal Eleven's intention to wind down the eye disease-focused company.
Cambridge, Massachusetts-based Eleven was left with no clinical candidates back in January after its topical drug isunakinra (EBI-005) failed in Phase III in a second indication, forcing the company to focus on its only named preclinical program – the injection EBI-031 for diabetic macular edema (DME) and uveitis
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