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Cardiovascular Drug Start-Ups

 
• By Marc Wortman

The cardiovascular drug marketplace has the dubious distinction of being the largest therapeutic category in terms of revenue, unmet need and mortality, while at the same time being the only area experiencing decreasing growth. Revenues will start to plummet starting in 2012 when the world's two largest CV drugs--Lipitor and Plavix--go generic. To help pharmas replace these and other aging drugs in their pipelines, Windhover's Therapeutic Alliances conference presents the "top 10" unpartnered clinical-stage cardiovascular programs.

When pharmaceutical dealmakers consider opportunities in the cardiovascular drug market, they reach for their antihypertensives—and they are probably generic medications at that. They face a scary choice between making very expensive, high-risk bets in hopes of bringing blockbuster products able to capture share in mature markets or risking loss of market share in the biggest product space of all. The right choice, however, may be to acknowledge an altered drug development landscape. An exit from the current dilemma will require rethinking the field.

The cardiovascular drug marketplace has the dubious distinction of covering the largest therapeutic category in terms of revenue ($89 billion...

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