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J&J, Achillion Could Set Six-Week Treatment Paradigm In HCV

 
• By Joseph Haas

Interim Phase IIa data of a triple combination from J&J and Achillion shows 100% SVR at end of treatment with a six-week dosing regimen. No currently approved HCV therapy has such a short treatment duration.

It's difficult to raise eyebrows with mid-stage data in genotype 1 patients several years into the hepatitis C combination therapy era, but Johnson & Johnson and Achillion Pharmaceuticals Inc. did just that on Sept. 9, with interim Phase IIa data showing that a three-drug, direct-acting antiviral (DAA) combo produced a 100% sustained virologic response (SVR) rate at end of a six-week dosing regimen.

Several analysts noted that no approved hepatitis C virus (HCV) regimen has a six-week duration of therapy, which could be...

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