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Mogamulizumab Nips At Adcetris’s Heels In CTCL After New Results

 
• By Ian Haydock

Mogamulizumab has met its primary survival endpoint in a comparative Phase III trial in cutaneous T-cell lymphoma, positioning the Kyowa Hakko Kirin product as a potential close follower to Adcetris in the second-line setting.

female scientist working with microscope

Kyowa Hakko Kirin Co. Ltd. says it plans to initiate discussions with regulatory authorities this year about pursuing marketing authorizations for mogamulizumab in cutaneous T-cell lymphoma (CTCL), following just-released positive top-line results from a comparative Phase III trial.

The new findings position the CCR4-targeting antibody as a likely “close follower“ in the CTCL setting to Adcetris (brentuximab vedotin), an antibody-drug conjugate being developed by Seattle Genetics Inc. and Takeda Pharmaceutical Co. Ltd

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Merck KGaA Braces For Volatility But Does Not Expect Europe To Budge On Pricing

 
• By Andrew McConaghie

Shares are hit as German conglomerate lowers revenue forecast.

Leo Roars To A Profit In Q1 As Adbry Grows In US

 
• By Kevin Grogan

The Danish firm's atopic dermatitis drug is holding its own despite strong competition from Sanofi/Regeneron’s Dupixent.

Lundbeck Lifted By Leap In Migraine Therapy Sales

 
• By Kevin Grogan

Vyepti revenues rise by nearly 70% in the first quarter.

‘Market Developments’ Persuade Galapagos To Rethink Spin-Off

 
• By Andrew McConaghie

CEO Paul Stoffels exits early to be succeeded by Henry Gosebruch, who will now consider ‘all options’ for the Belgian firm as it tries to claw back investor confidence.

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Most Favored Nation Policy ‘Lazy, Misguided,’ But US Price Reforms Politically ‘Inevitable’

 
• By Cathy Kelly

Policy experts and pharma executives react to President Trump’s executive order on “equalizing” drug prices between the US and comparable nations at the ISPOR 2025 conference.

Merck KGaA Braces For Volatility But Does Not Expect Europe To Budge On Pricing

 
• By Andrew McConaghie

Shares are hit as German conglomerate lowers revenue forecast.

Leo Roars To A Profit In Q1 As Adbry Grows In US

 
• By Kevin Grogan

The Danish firm's atopic dermatitis drug is holding its own despite strong competition from Sanofi/Regeneron’s Dupixent.