Shire CEO Says Lanadelumab Results Vindicate Dyax Buy, M&A Strategy

Shire's CEO is savoring a personal victory after Phase III data for lanadelumab in acute HAE replicated impressive Phase Ib trial results that underpinned his 2015 decision to buy Dyax.

Angioedema
Shire's lanadelumab Shines In Phase III Trial Data For Acute HAE

Hugely positive Phase III top-line data for Shire PLC’s monoclonal antibody product lanadelumab in acute HAE represents "an historic event" for the rare disease specialist, vindicates its purchase of Dyax Corp. in late 2015, and keeps the asset on track for eventual "blockbuster" status, CEO Flemming Ornskov told Scrip in an interview.

He was commenting after the world's biggest rare disease specialist announced that its Phase III HELP trial, evaluating lanadelumab (or SHP643), a long-acting therapy for hereditary angioedema, met all primary and

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