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Janssen's Zytiga Shines At ASCO But Prostate Cancer Pipeline Progress May Dampen Impact

 
• By Lucie Ellis-Taitt

Janssen reported treatment altering Phase III data at ASCO 2017 for a new Zytiga combination targeting hormone-naïve metastatic prostate cancer patients – but the triple regimen's relevance might be short-lived as momentum builds in the late-stage pipeline.

Conference
Janssen reports data for Zytiga triplet in early-stage prostate cancer at ASCO 2017 • Source: Mary Jo Laffler

Janssen Pharmaceutical Cos. (a Johnson & Johnson company) reported positive Phase III data for Zytiga (abiraterone acetate) in hormone-naïve metastatic prostate cancer, providing a non-chemotherapy option for patients that is expected to change the standard of care. However, the market impact of Janssen's triple therapy could be limited due to a busy late-stage drug pipeline that includes novel mechanisms of action.

Data from the Phase III LATITUDE study, the subject of the June 4 plenary session at the American Society of...

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