Safety Issues Not Dampening AbbVie Optimism For Humira Successors

AbbVie is optimistic that its JAK1 inhibitor upadacitinib and anti-IL23 candidate risankizumab can increase its autoimmune market share, doubting a thromboembolic class effect for JAK inhibitors.

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AbbVie Inc. remains optimistic, despite some outside safety concerns, that its late-stage immunology drug candidates can increase its market share in autoimmune disease at a time when its top-selling powerhouse Humira (adalimumab) is facing increased competition from both biosimilars and new branded agents.

AbbVie talked up a number of pipeline milestones expected in the second half of 2017 during its July 28 second...

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