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Non-Inhibitor Data Secure Roche's Competitive Position In Hemophilia A

 
• By Mandy Jackson

Roche's Genentech reported positive top-line Phase III results for Hemlibra in a second hemophilia A population – patients without inhibitors – just four days after its approval for patients with inhibitors, which will broaden the product's market and may improve its competitive position.

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Roche's Genentech Inc. reported positive top-line results for Hemlibra (emicizumab-kxwh) in the treatment of hemophilia A patients who do not have inhibitors of factor VIII and the data appear to boost the newly approved product's competitive position against the high-cost standard of care.

Detailed data from the Phase III HAVEN 3 clinical trial, which will be presented at a future medical meeting, may shed more light on whether Hemlibra can steal significant market share from established factor VIII clotting factors from Shire PLC, Novo Nordisk AS and other major hemophilia players. (Also see "Competition Coming For Hemophilia Franchises, But Will Patients And Payers Embrace New Drugs?" - Scrip, 16 March, 2017

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