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Start-Up Obsidian Gets $49.5m To Determine How And When To Activate CAR-T Cells

 
• By Mandy Jackson

Obsidian CEO Michael Gilman described the company's technology – which allows CAR-T cells and other therapies to be activated by available small molecule drugs – as being able to modulate the effective yet toxic therapies by dialing down, turning up or shutting off the treatments as needed.

3d illustration of T cells or cancer cells

Obsidian Therapeutics Inc. raised $49.5m in Series A venture capital to develop its technology for inserting a synthetic tag into chimeric antigen receptor T cell (CAR-T) therapies so that the they can be activated or deactivated as needed for efficacy or safety.

That's just one of three initial uses for Obsidian's technology that CEO Michael Gilman described in an interview with Scrip on Dec. 6 when the company announced its Series A...

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