AstraZeneca Keeps R&D Focus, Spins Out Phase II Neuromyelitis Optica MAb Into New Biotech

Six early-stage biologics with potential to treat inflammation and auto-immunity disorders have been spun out of AstraZeneca's biologics arm, MedImmune, into a stand-alone Chinese investor-backed company, Viela Bio, underlining the commitment of the big pharma to its three areas of therapeutic focus.

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Spinning off non-core assets has been a feature of AstraZeneca's business development • Source: Shutterstock

A biologic, inebilizumab, in Phase II for the treatment of an autoimmune disease, neuromyelitis optica, is the lead compound for a new stand-alone company, Viela Bio, spun-out of AstraZeneca PLC's biologics arm, MedImmune LLC, with financing from a group of Chineseprivate equity funds. The new company is helmed by CEO Bing Yao, previously head of MedImmune's respiratory, inflammation and autoimmunity (RIA) innovative medicines unit.

"Auto-immune diseases are a group of around 80 disorders, the majority of which have no specific therapies, and they represent a therapeutic area of high unmet need," Bing explained to Scrip

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