Pfizer May Enjoy Blockbuster Cardiomyopathy Success With Tafamidis

02 Apr 2018

Although tafamidis has been stalled at FDA for transthyretin-mediated polyneuropathy, Pfizer may have found a different path toward US approval with cardiovascular outcomes data in cardiomyopathy.

Pfizer Inc. may have an unexpected blockbuster opportunity on its hands, as it reported significant cardiovascular outcomes data March 29 from a Phase III study of tafamidis meglumine in transthyretin-mediated cardiomyopathy. Approved overseas as Vyndaqel, tafamidis has been tied up since 2012 at US FDA for the related indication of familial amyloid polyneuropathy (FAP).

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