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More IDO Issues: NewLink Drops Pancreatic Cancer Indication For Indoximod

 
• By Lucie Ellis-Taitt

NewLink has scrapped plans to explore its IDO inhibitor in pancreatic cancer – more bad news for a drug class that has suffered several setbacks recently.

Juggling
NewLink juggles too many indoximod options; drops pancreatic cancer program • Source: Shutterstock

NewLink Genetics Corp. has “deprioritized” pancreatic cancer and will not proceed with a planned Phase II study testing its lead product indoximod with AstraZeneca PLC's Imfinzi (durvalumab), the company said during its first-quarter earnings announcement.

This follows on from news last month that NewLink had halted the Phase III Indigo301 study of indoximod in combination with PD-1 inhibitors for patients with advanced melanoma. NewLink plans...

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