Merck KGaA R&D Head: Biomarker Approach 'Further Validated' At ASCO

Luciano Rossetti says Germany's Merck is likely to partner M7824 bifunctional immunotherapy, and go solo with tepotinib.

Tumor marker
Merck KGaA is using biomarkers to select patients for testing Tepotinib and M7824. • Source: Shutterstock

Merck KGAA created an excited stir at ASCO with impressive presentations on its targeted tepotinib and its M7824 TGF-beta trap therapies in non-small cell lung cancer. Its biopharma R&D head tells Scrip the German group wants to develop and commercialize the former on its own, and partner M7824 with a big pharma.

At this year's American Society of Clinical Oncology (ASCO) annual meeting in Chicago, Darmstadt-based Merck unveiled early data from its Phase II VISION trial showing promising initial results using tepotinib...

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