This is a key moment in time, says Annalisa Jenkins, executive chair of Silence Therapeutics PLC, for both the company and the interfering RNA (RNAi) space, likening it to the development of antibody technology several years ago.
The crux of the science lies at the ability of RNA interference to inhibit gene expression by neutralizing targeted mRNA molecules. The space is hotting up, with Alnylam Pharmaceuticals Inc.’s selective RNAi agent, patisiran, expected to be reach the market for the treatment of hATTR amyloidosis in the near future
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