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GSK Makes I-O Move With Merck KGaA Deal Worth Up To €3.7bn

 
• By Kevin Grogan

Already working with Pfizer on the immunotherapy Bavencio, Merck KGaA has bagged another big pharma player in GSK to progress what has been heralded by analysts as the German group's oncology game changer, M7824, which combines two powerful and synergistic anticancer mechanisms into one molecule.

Brainstorming
Merck KGaA and GSK See Bright Future For M7824 • Source: Shutterstock

GlaxoSmithKline PLC's return to the oncology space has been confirmed by the UK major making a hefty €300m upfront payment to get access to Merck KGAA's bifunctional immunotherapy M7824 (bintrafusp alfa).

M7824 has been designed to simultaneously target two immuno-suppressive pathways - transforming growth factor-β (TGF-β) trap and an anti-programmed cell...

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More from Immuno-oncology

CEO Underlines AstraZeneca’s Increasingly US-Centric Growth Plans

 
• By Andrew McConaghie

Its multibillion dollar investment demonstrates the importance of the US to AstraZeneca, with half of its targeted $80bn revenues by 2030 set to come from the country, Pascal Soriot said as it presented strong second-quarter results.

Dispatch Uses ‘Flare’ To Send CAR-Ts To Solid Tumors

 
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Sino Biopharm Scoops LaNova In Chinese Pharma’s Biggest Biotech Buyout So Far

 
• By Dexter Jie Yan

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More from Anticancer

GSK’s Blenrep US Setback Could Go From Bad To Worse

 
• By Sushmita Panda

With a US approval any time soon now looking unlikely, analysts are revising Blenrep’s peak sales guidance downwards.

Boehringer Ingelheim Expects Two Key Approvals In Second Half Of 2025

 
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Dispatch Uses ‘Flare’ To Send CAR-Ts To Solid Tumors

 
• By Alaric DeArment

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