Lilly's Trulicity Shows Unique Cardiovascular Outcomes Benefit, Albeit A Modest One

At the ADA annual meeting, Lilly reported positive results from REWIND, a cardiovascular outcomes trial studying the GLP-1 agonist Trulicity in a broad population of patients with and without established CV disease.

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Trulicity shows a benefit in cardiovascular outcomes • Source: Shutterstock

Eli Lilly & Co. reported the first detailed results from a cardiovascular outcomes trial for the GLP-1 receptor agonist Trulicity (dulaglutide) at the American Diabetes Association's annual meeting on 9 June in San Francisco, showing treatment with Trulicity resulted in a significant 12% reduction in major cardiovascular events in a uniquely broad patient population. But the results were more modest than some investors had expected.

Trulicity competes in a crowded class, so it's unclear if the data will give Trulicity a substantial commercial boost as it works to maintain its market-leading position against competition from Novo Nordisk AS's Ozempic (semaglutide), which

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