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ASH First Look: CAR-T Therapies Against BCMA, CD19 And More

 
• By Mandy Jackson

CAR-T therapies from Janssen, Celgene and others will get a lot of attention at the annual hematology meeting, including candidates with novel constructs and targets. 

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BCMA CAR-T still is a hot topic, but novel therapies advance at ASH.

T-cell therapies once again will be a hot topic at this year’s American Society of Hematology annual meeting 7-10 December in Orlando, FL, ranging from the latest round of BCMA-targeting chimeric antigen receptor T-cell therapy results in multiple myeloma to very early first-in-human results for the first CRISPR/Cas9 gene-edited T-cell therapy.

Data for CAR-T therapies, bispecific antibodies and other candidates targeting B-cell maturation antigen (BCMA) for the treatment of multiple myeloma...

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