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Insmed Goes Full Steam Ahead With Bronchiectasis Candidate

Top-Line Phase II Data Impress For INS1007

 
• By Alexandra Shimmings

Insmed shares got a 40% boost as the company announced plans to move into Phase III this year with its potential first-in-class candidate for the lung disease.

Deforestation_Lungs
• Source: Shutterstock

Insmed Inc. is to take its potential first-in-class product INS1007 into late-stage trials on the basis of positive top-line data from its Phase II WILLOW study in adults with non-cystic fibrosis bronchiectasis (NCFBE), a potential billion dollar market opportunity. Its shares shot up by 40% to close at $28.88 on the NASDAQ on 3 February following the news.

INS1007, an oral, selective, reversible inhibitor of dipeptidyl peptidase 1 (DPP1), hit its primary and key secondary endpoints in the 256-patient trial,

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