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Sanofi And Regeneron Initiate 400-Patient Coronavirus Trial With Kevzara

 
• By Jessica Merrill

The Phase II/III trial will begin enrolling patients in the US immediately, with Regeneron taking the lead in US development and Sanofi leading ex-US trials. 

COVID-19 SARS,Coronaviridae , SARS-CoV, SARSCoV, virus 2020 , MERS-CoV ,chinese virus 2019-nCoV
There is early evidence IL-6 drugs help drive down inflammatory immune response

Sanofi and Regeneron Pharmaceuticals Inc. have initiated a clinical trial program evaluating the interleukin-6 receptor blocker Kevzara (sarilumab) in patients with COVID-19 in the US, the companies announced on 16 March. Regeneron said it hopes to have data from the Phase II/III trial quickly – it expects to dose the first of 400 patients “early this week,” a spokesperson told Scrip.

Regeneron did make clear that the companies are working with the US Food and Drug Administration (FDA) and the Biomedical Advanced Research and Development Authority (BARDA) to facilitate the quick start of the trial “so that

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