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Genmab And Seattle Genetics Progress Cervical Cancer ADC

 
• By Alexandra Shimmings

Topline Phase II data for the antibody-drug conjugate tisotumab vedotin put it on a swift path towards approval in cervical cancer.    

Cervical cancer
Cervical cancer cell • Source: Shutterstock

Genmab AS and Seattle Genetics Inc. should be able to file for approval of their antibody-drug conjugate tisotumab vedotin on the basis of a Phase II trial that has just reported positive topline results in advanced cervical cancer.

The ongoing 101-patient single-arm innovaTV 204 trial is testing tisotumab vedotin given every three weeks in patients with recurrent or metastatic cervical cancer who were previously treated with doublet chemotherapy with

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