Bayer's Finerenone Hints Positive In Diabetic Kidney Disease

Could Provide Competition For SGLT2 Inhibitors

The Phase III FIDELIO trial of finerenone has been a success but analysts want to see some actual data before declaring it an unqualified one.

Bayer Pharma AG, Administration and laboratory buildings of Bayer HealthCare Pharmaceuticals in Berlin-Wedding on June 14, 2017, Germany - Image
The German major has high hopes for finerenone • Source: Shutterstock

Bayer AG has been boosted by positive topline data on finerenone, one of the lead assets in its pipeline, which showed that the drug lowered the risk of renal and cardiovascular (CV) events in patients with chronic kidney disease (CKD) and type 2 diabetes.

The German group has given the first insight into the 5,700-patient Phase III study FIDELIO-DKD which revealed that finerenone significantly reduced the combined primary endpoint of CKD progression, kidney failure or kidney death versus placebo when added to standard of care

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