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Moderna’s COVID-19 Vaccine Spurs Immune Response In All Phase I Subjects At All Doses

 
• By Mandy Jackson

Neutralizing antibodies were seen in all 45 people injected across three dose levels in the first-in-human study. The middle dose of 100mcg will be tested in the company’s Phase III trial starting 27 July.

3d rendering: Vaccination against new Corona Virus SARS-CoV-2: A glass with vaccination and a syringe behind it. The word vaccination in English, Spanish, French and German on the label. Copy space
Moderna's vaccine generated antibodies that can neutralize SARS-CoV-2 in all 45 Phase I participants • Source: Shutterstock

A more complete set of Phase I results for Moderna, Inc.’s vaccine mRNA-1273 against COVID-19 have shown that all 45 patients treated across all three dosing levels generated antibodies capable of neutralizing SARS-CoV-2, the novel coronavirus.

Chief medical officer Tal Zaks told Scrip that these data, published in the New England Journal of Medicine on 14 July, reaffirm Moderna’s decision to take the vaccine into a company-sponsored Phase III clinical trial at the middle dose tested

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