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Anti-Aging Firm Unity Stumbles At First Major Hurdle

Hit By Lead Drug Failure In OA

 
• By Alexandra Shimmings

Unity is set to drop its lead product based on its senescent cell science as it fails in a Phase II study in osteoarthritis of the knee. Focus switches to ophthalmic product.    

Leaves
Can Unity turn back time? • Source: Shutterstock

UNITY Biotechnology, Inc.’s lead product, UBX0101, has hit the buffers in a Phase II osteoarthritis trial, raising some concern over the viability of its anti-aging thesis.

The 183-patient study found no difference between the p53/MDM2 interaction inhibitor and placebo in patients with moderate-to-severe painful osteoarthritis (OA)...

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Pipeline Watch: Eight Approvals And Ten Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.