Novartis Novel STAMP Inhibitor Passes First Phase III Test In CML

Asciminib Could Be New Option For Resistant Patients

Phase III data for asciminib suggest it could provide a new avenue of therapy for chronic myeloid leukemia patients who are running out of treatment options.    

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New Therapy For Advanced Patients • Source: Shutterstock

The first Phase III study of Novartis AG’s potential treatment option for chronic myeloid leukemia, asciminib (ABL001), has met its primary endpoint, topline data show.

The 234-patient ASCEMBL trial showed a significantly better major molecular response (MMR) rate at 24 weeks with asciminib (ABL001) versus Pfizer’s BCR-ABL and src tyrosine kinase inhibitor, Bosulif (bosutinib)

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