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Coronavirus Update: Moderna Ready For Interim Analysis, Brazil Resumes SinoVac Trial

Plus a plant-derived COVID-19 vaccine moves into Phase II/III

 
• By Scrip Team

Moderna's vaccine has reached the requisite number of cases to trigger a Phase III interim analysis and Brazil allows SinoVac's trial to resume after a serious adverse event, but AstraZeneca's Calquence fails to show any benefit in hospitalized COVID-19 patients. Medicago and GSK also report vaccine progress and the RDIF strikes another production deal.  

Coronavirus
Trial Progress And New Production Deals • Source: Shutterstock

The Phase III study of Moderna, Inc.’s mRNA vaccine against SARS-CoV-2 has reached the threshold of cases needed to perform the first interim analysis.

In an 11 November statement, Moderna said it expected to submit data on more than 53 cases from the COVE study of the mRNA-1273 vaccine – the trigger point for an interim analysis – to the data safety monitoring board (DSMB), which will then analyze the data and issue a recommendation. The company remains blinded to whether the participants received the vaccine or placebo

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