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Another Failure For Biohaven’s Troriluzole

Alzheimer’s Study Misses

 
• By Alexandra Shimmings

Biohaven’s investigational glutamate modulator troriluzole did not improve symptoms in patients with mild-to-moderate disease, adding to the list of failures in Alzheimer’s disease, as well as for the product itself.    

• Source: Shutterstock

Biohaven Pharmaceutical Holding Company Ltd.’s glutamate modulator troriluzole has failed a Phase II/III study in Alzheimer’s disease, top-line data show.

The product was no better than placebo at 48 weeks as measured by the study's prespecified co-primary endpoints on the Alzheimer's disease assessment scale-cognitive subscale 11 (ADAS-cog) and the clinical dementia

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