Regeneron Antibodies Prevent Symptomatic COVID-19 In Interim Phase III Data

Efficacy Data On Casirivimab/Imdevimab In Mutant Strains Forthcoming

The company said data show a lower overall infection rate and no symptomatic infections among participants receiving the drug, compared with placebo.

Antibodies immunoglobulins attacking coronavirus covid-19 influenza virus cell, 3D immune system medical illustration background. Corona virus 2019-ncov sars cell, igm. Coronavirus sars-cov-2 disease
Interim data from Regeneron's Phase III study show its antibody cocktail is effective at preventing symptomatic COVID-19. • Source: Shutterstock

Regeneron Pharmaceuticals, Inc.'s two-antibody cocktail treatment for COVID-19 could potentially present a therapeutic option for people with compromised immune systems living with those who are infected, based on interim Phase III data the company announced on 26 January showing that it reduced symptomatic infections.

If the confirmatory data – expected early in the second quarter – are also positive, casirivimab/imdevimab (REGEN-COV or REGN-COV) would become the second antibody therapy to double as a treatment and a preventive drug for SARS-CoV-2 infection. The combination was granted emergency use authorization by the US Food and Drug Administration in November for use in patients over 12 with mild-to-moderate disease at risk of developing serious disease or needing hospitalization

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from R&D

Pipeline Watch: Eight Approvals And Nineteen Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.

Merck KGaA Braces For Volatility But Does Not Expect Europe To Budge On Pricing

 

Shares are hit as German conglomerate lowers revenue forecast.

Leo Roars To A Profit In Q1 As Adbry Grows In US

 
• By 

The Danish firm's atopic dermatitis drug is holding its own despite strong competition from Sanofi/Regeneron’s Dupixent.

Lundbeck Lifted By Leap In Migraine Therapy Sales

 
• By 

Vyepti revenues rise by nearly 70% in the first quarter.

More from Scrip

Regeneron Wins PCSK9 Court Battle Against Amgen

 

A federal court jury found Amgen liable for violating antitrust laws in allegedly preventing Praluent from competing against Repatha.

Lupin CEO On Trump’s Most Favored Nation Policy, Tariffs, Firm’s Five-Year Plan

 
• By 

Lupin CEO Vinita Gupta speaks on Trump’s most favored nation policy, the Inflation Reduction Act’s “pill penalty” and other developments in the US, a major market for the company. The company also outlines a five-year plan focused on complex generics and technology platforms.

Novo Nordisk’s CEO Forced Out After Falling Behind In GLP-1 Battle

 

Company surprises investors with Jørgensen's exit but insists its strategy will not change.