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Novartis Hit By Canakinumab NSCLC Miss

Interleukin-1 Beta Inhibitor Fails To Improve Survival

 
• By Kevin Grogan

The Swiss firm's canakinumab has proved to be an effective treatment for several inflammation-driven rare conditions but disappointment from the CANOPY-2 trial suggests that cancer will follow cardiovascular as an indication where the therapy falls by the wayside.

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CANOPY-2 misses the target • Source: Shutterstock

Having failed to add a cardiovascular indication for canakinumab, Novartis AG's hopes of progressing the anti-inflammatory agent in oncology have been hit by another failure, this time in a late-stage trial for non-small cell lung cancer (NSCLC).

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