Adagio Therapeutics, Inc. is pushing its way into an increasingly crowded and narrow space for COVID-19 therapeutics, with plans for rapid development of ADG20, an intramuscular monoclonal antibody designed to keep patients from progressing to severe disease.
The Waltham, MA-based Adagio said 19 April that it had completed a series C financing worth $336m, which it plans to use to develop ADG20. The antibody was designed for broad treatment of coronaviruses and has shown preclinical activity against wild-type SARS-CoV-2 and several variants of concern, including the B.1.1.7 UK variant, the B.1.351 South African variant and the P.1 Brazilian variant
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