Could Start-Up Adagio’s COVID-19 Antibody Have A Fighting Chance?

The company announced a $336m series C round, six months after it raised an $80m series B, to support development of an easily administered treatment ADG20.

Antibodies immunoglobulins attacking coronavirus covid-19 influenza virus cell, 3D immune system medical illustration background. Corona virus 2019-ncov sars cell, igm. Coronavirus sars-cov-2 disease
Adagio announced that it had raised a $336m series C funding round for its coronavirus therapeutics • Source: Shutterstock

Adagio Therapeutics, Inc. is pushing its way into an increasingly crowded and narrow space for COVID-19 therapeutics, with plans for rapid development of ADG20, an intramuscular monoclonal antibody designed to keep patients from progressing to severe disease.

The Waltham, MA-based Adagio said 19 April that it had completed a series C financing worth $336m, which it plans to use to develop ADG20. The antibody was designed for broad treatment of coronaviruses and has shown preclinical activity against wild-type SARS-CoV-2 and several variants of concern, including the B.1.1.7 UK variant, the B.1.351 South African variant and the P.1 Brazilian variant

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