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Ipsen Buys Into BAX Inhibitor, Targeting Certain Cancers

Ipsen And BAKX Will Develop Latter’s BCL-2 Inhibitor

 
• By Sten Stovall

Ipsen has inked a worldwide collaboration pact with BAKX Therapeutics to research, develop, manufacture and commercialize the biotech’s asset BKX-001 as a potential treatment for leukemia, lymphoma and solid tumors.

Investigational BKX-001 is an oral small-molecule activator of BAX • Source: Alamy

Continuing its search for promising external compounds, Ipsen SA has signed an exclusive global pact with BAKX Therapeutics to research, develop, manufacture and commercialize the US biotech’s investigational therapy BKX-001 as a potential treatment for leukemia, lymphoma and solid tumors, by targeting the B-cell lymphoma-2 (BCL-2) family of proteins.

The alliance reflects Ipsen’s continued aim to strengthen its pipeline, specifically in the oncology and neurology spaces. It comes shortly after the Paris-based pharma agreed with IRLAB Therapeutics AB to exclusively develop mesdopetam, a drug discovered by the Swedish biotech against dyskinesia induced by levodopa, for use in treating Parkinson's disease

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