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Novartis Scores Another CSU Success With Remibrutinib

Oral BTK Inhibitor Controls Itching And Hives In Phase IIb

 
• By Kevin Grogan

The Swiss group believes that remibrutinib, as well as its investigational IgE antibody ligelizumab, will complement standard of care Xolair and help it build a strong franchise for chronic spontaneous urticaria.

Urticaria
Intense itching is a feature of urticaria

Novartis AG is looking to cement its leading position in chronic spontaneous urticaria and has presented promising mid-stage data on remibrutinib, which the Swiss major describes as "a potentially best-in-class oral Bruton's tyrosine kinase (BTK) inhibitor."

Phase IIb data has been presented at the European Academy of Dermatology and Venereology (EADV) congress which evaluated remibrutinib in chronic spontaneous urticaria (CSU) patients inadequately controlled with antihistamines. In...

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