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UCB Moves Up Myasthenia Gravis Pipeline With Rozanolixizumab Win

Slips Into Second Place Behind Argenx's Efgartigimod

 
• By Kevin Grogan

Argenx's efgartigimod could very soon become the first anti-FcRn agent to get approval for generalized myasthenia gravis but UCB’s rival therapy rozanolixizumab for the rare muscular disease is nearly ready to be filed with regulators.

UCB flag
• Source: UCB

UCB S.A. has moved closer to becoming a major player in the generalized myasthenia gravis (gMG) space with rozanolixizumab, one of the Belgian group's two late-stage candidates for the rare autoimmune disease, hitting its goals in a late-stage trial.

The Brussels-headquartered firm has revealed that the Phase III MycarinG study of rozanolixizumab met its primary endpoint, demonstrating a significant change from baseline in the Myasthenia Gravis-Activities of Daily Living (MG-ADL) total score at day 43

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