Bayer Consolidates Next-Generation Gene Editing Focus With Mammoth Deal

Pays $40m

The German major will collaborate with the US biotech to develop CRISPR gene-editing therapies, solidifying its interest in next-generation therapeutics.  

Genetic Engineering, Scientist viewing cells in a culture jar with a DNA profiles on a screen in the background illustrating gene editing
Bayer Will Gain Access To Mammoth’s Ultra-Small Cas enzymes. • Source: Alamy

Bayer AG is putting more heft behind its cell and gene therapy R&D portfolio by paying $40m upfront to Mammoth Biosciences to use its in vivo CRISPR-based gene-editing technology to develop therapies for five undisclosed indications, with an initial focus on liver-targeted diseases.

“Bringing together Mammoth’s novel CRISPR systems with our existing gene augmentation and our induced pluripotent stem cell (iPSC) platforms will allow us to unleash the full potential of our cell and gene therapy

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