Mirati Spies ‘First-In-Class’ Chance For KRAS Inhibitor In Pancreatic Cancer

Adds To Colorectal Cancer Opportunity

While chasing Amgen’s Lumakras in NSCLC, Mirati looks to now have an edge in two other tumor types.

Mirati Therapeutics
Mirati is expecting its first approval for adagrasib by mid-2022 in NSCLC - but is looking to carve out a niche in CRC and GI cancers ahead of Amgen. • Source: Mirati Therapeutics

Mirati Therapeutics is continuing its bid to make its KRAS inhibitor candidate adagrasib a future market leader, presenting new Phase II data in patients with pancreatic and other gastrointestinal tumors.

Amgen’s Lumakras (sotorasib) became the first marketed KRAS inhibitor in May 2021, following a US approval in non-small cell lung cancer (NSCLC), but Mirati believes its drug will emerge as

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