Magrolimab Falls Off The Fast Track As Gilead Reveals New Clinical Holds

Biktarvy Settlement Totals $1.25bn Up Front, 3% US Bictegravir Royalty

The company said in its fourth quarter earnings report that it would not seek accelerated approval for the drug, while it also settled an HIV drug-related intellectual property lawsuit with GSK/ViiV.

Stopping the domino effect concept
Gilead announced Q4 and full year 2021 earnings on 1 February • Source: Alamy

Gilead Sciences, Inc. is calling off its effort to pursue accelerated approval of magrolimab in myelodysplastic syndrome (MDS), while the US Food and Drug Administration has placed partial clinical holds on additional Phase II trials of the drug, in multiple myeloma and diffuse large B-cell lymphoma (DLBCL), the company said in its fourth quarter earnings report.

Gilead also reached a settlement with GlaxoSmithKline plc and ViiV Healthcare regarding the HIV drug Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide), whereby the company will pay GSK and ViiV $1

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