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Anavex Reveals Positive Phase III Data In Rett Syndrome But A Surprise Endpoint

 
• By Jessica Merrill

The endpoint used in the AVATAR trial was different than the one investors had expected; management said the change was made to satisfy the US FDA.

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Anavex took a different direction with a Phase III trial • Source: Alamy

Anavex Life Sciences Corp. announced positive Phase III data from a clinical trial testing blarcamesine (Anavex 2-73) in patients with the debilitating neurodevelopmental disorder Rett syndrome, but the endpoint used in the study was different from the one investors had expected – a change that management said was based on guidance from the US Food and Drug Administration.

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