Optinose Looking For A Partner To Optimize Big Opportunity In Chronic Sinusitis

With positive Phase III data for its Xhance (fluticasone propionate) nasal spray in chronic sinusitis, Optinose believes it is poised to expand the target market for the drug 10-fold.

Optinose eyes a big growth opportunity with new data • Source: Shutterstock

OptiNose, Inc. believes it is poised to have the first drug approved by the US Food and Drug Administration for a broad indication for chronic sinusitis (CS). The company reported positive Phase III data on 13 June from a second study testing its Xhance (fluticasone propionate) nasal spray in individuals with chronic sinusitis without nasal polyps.

The corticosteroid is already approved for the treatment of nasal polyps, as are some other medications like Sanofi/Regeneron Pharmaceuticals, Inc.'s IL-4/IL-13 inhibitor Dupixent (dupilumab), which is approved as an add-on maintenance treatment in adults with inadequately controlled chronic rhinosinusitis with nasal polyps

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