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Amid Expected Enhertu Entry, Chinese Domestic ADC Developers Race To Market

'Fast-Follower' Strategy?

 
• By Dexter Jie Yan

12 biotechs in China are preparing to compete for domestic market share for their home-grown HER2-targeted antibody-drug conjugates amid Enhertu’s in-roads in the country.

Chinese developers are flocking to ADC drugs after seeing chances of blockbuster success.
At least 12 HER2-targeted ADCs in clinical studies in China • Source: Alamy

Antibody-drug conjugate (ADC) developers in China are mulling over ways to put up a fight for future domestic market share, given that Daiichi Sankyo Co., Ltd./AstraZeneca PLC’s blockbuster ADC Enhertu (trastuzumab deruxtecan) is set to make inroads in the country over the coming months.

As evidenced by recent partnerships forged with US drug makers to out-license global rights to Claudin 18.2-targeted ADC candidates, some Chinese bioventures are increasingly looking to overseas markets for their...

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