New Data Position Lazertinib As Strong Contender In 1L NSCLC

Potential Tagrisso Challenger?

Yuhan’s oncology drug lazertinib is set to expand its indications in Korea to the first-line treatment of EGFR mutation-positive advanced NSCLC, based on new top-line Phase III data showing clinical benefits for all patient sub-groups.

lung cancer
New Indication Filing for Lazertinib Expected In Korea in Q1 '23 • Source: Shutterstock

South Korea's Yuhan Corporation has unveiled promising top-line Phase III data for its novel cancer drug lazertinib in the first-line treatment of epidermal growth factor receptor (EGFR) mutation-positive, advanced non-small cell lung cancer (NSCLC), concluding the drug will be competitive as a monotherapy and raising hopes for a second standard-of-care option for a form of the malignancy seen more frequently in Asia.

The top-line findings from the LASER301 study, presented at the ESMO (European Society for Medical Oncology) Asia Congress held in Singapore on 2-4 December, showed the oral EGFR tyrosine kinase...

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