Prometheus Phase II Data For Novel TL1A Inhibitor Impresses On Efficacy

The company plans to move PRA023 forward into Phase III studies based on positive Phase II safety and efficacy data in UC and Crohn's disease, positioning Prometheus in a race with Roivant.

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Prometheus hit the mark on a key Phase II trial • Source: Shutterstock

Prometheus Biosciences, Inc is moving PRA023 into Phase III clinical studies for ulcerative colitis and Crohn's disease after two Phase II studies read out positively and boosted confidence that the novel tumor necrosis factor-like ligand 1A (TL1A) inhibitor could be a potential first-in-class treatment option for the two immune-mediated diseases.

The Phase II efficacy data surpassed investor expectations and led the company's stock price to catapult

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