Bellicum Weighs Options After Hitting Brakes On CAR-T Program

An analyst suggested the company might end up selling its technology to a large pharma player, citing AstraZeneca’s $68m buyout of LogicBio in October as a precedent.

Bellicum is weighing options after announcing it would discontinue its two clinical CAR-T programs • Source: Shutterstock

It is unclear what kinds of strategic alternatives Bellicum Phamaceuticals, Inc. is considering now that the company has decided to discontinue its two chimeric antigen receptor T-cell (CAR-T) therapy programs in solid tumors and assess a different path forward. The company moved to end its clinical trial programs due to toxicity as well as limited financial resources, although an analyst suggested its best strategy may be to sell its assets and know-how, pointing to a similar deal that occurred in October.

Bellicum said 14 March that it would discontinue the Phase I/II clinical trials of BPX-601 in metastatic castration-resistant prostate cancer (mCRPC) and BPX-603 in HER2-positive solid tumors

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