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Lexicon’s Sotagliflozin Succeeds In Heart Failure Following Disappointment In Diabetes

 
• By Joseph Haas

Lexicon gets broad indication across heart failure for its dual SGLT1/2 inhibitor, which will be positioned against Lilly/BI’s Jardiance and AstraZeneca’s Farxiga.

Approval
Lexicon gets sotagliflozin approval in heart failure after missing in diabetes • Source: Shutterstock

After being thwarted in trying to bring its dual SGLT1/2 inhibitor sotagliflozin to market for type 1 diabetes, Lexicon Pharmaceuticals, Inc. got a big win with the drug with US Food and Drug Administration approval for heart failure with a broad label across the spectrum of heart failure, including decompensated patients who have been recently stabilized, which will be a unique claim versus the other SGLT inhibitors.

Lexicon said the drug, to be branded Inpefa, should be available in June and will priced in line with the

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