Acelyrin, Inc. was a rare success story in this year’s moribund biotech IPO market, raising $540m on the NASDAQ in May in the third-largest biotech flotation since 2018. Investors who piled in at the IPO price of $18 initially did nicely; the shares closed 11 September at $27.90.
Acelyrin Goes From Float To Sink
A catastrophic late-stage clinical failure wipes 60% off the group’s value – and boosts a rival.

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