Gilead Adds To Virology Focus Through 12-Year Collaboration With Assembly

Gilead gets option rights to Assembly’s entire virology pipeline, including future assets, for herpesvirus and hepatitis B and D. The deal provides financial stability and opt-in potential for Assembly.

Virus. Digital illustration of Herpes virus. Realistic image of microbe, microorganism, microscopic view - Illustration
Gilead looks to Assembly for novel HSV, hep B and hep D candidates

Gilead Sciences, Inc. has historically focused on virology, with blockbuster products for HIV, hepatitis C and hepatitis B, but more recently has looked to broaden its therapeutic focus, particularly into oncology. Now the company appears to be re-emphasizing its core strength, signing a 12-year collaboration on 17 October with Assembly Biosciences, Inc. that will give it opt-in rights on all current and future pipeline candidates across herpesvirus, hepatis B virus (HBV) and hepatitis D.

Key Takeaways
  • Gilead makes $100m upfront commitment, including an equity purchase, in Assembly to collaborate on novel antivirals for herpesvirus, hep B and hep D.

  • Under the agreement, Gilead can opt in to take over any Assembly pipeline asset, including future R&D discoveries, over a 12-year term

Following some development setbacks in 2020 and 2021 that left it with nothing currently in active clinical development, Assembly has been attempting its own transformation, going back to R&D to identify novel approaches to viral diseases. (Also see "Assembly Looks To Quickly Move Past ABI-H2158 Discontinuation" - Scrip, 2 September, 2021

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