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Riding US Approval, Junshi, Coherus Swing For PD-1 Combo Therapy Partnerships

 
• By Dexter Jie Yan

Antibodies targeting TIGIT, IL-27, CCR8 and BTLA from the Chinese and US firms are among the first batch of combination candidates expected to expand the indications of anti-PD-1 antibody Loqtorzi beyond the rare condition of nasopharyngeal carcinoma.

business partnership
Junshi/Coherus’s anti-PD-1 Loqtorzi gets into swing of partnering for combination therapies • Source: Shutterstock

Having successfully landed their anti-PD-1 Loqtorzi (toripalimab) in the US, Shanghai Junshi Biosciences Co., Ltd. and Coherus BioSciences, Inc. are set to jump-start a partnership bonanza for potential combination therapies using the immuno-oncology drug as the backbone.

Key Takeaways

  • Junshi and Coherus’s anti-PD-1 Loqtorzi (toripalimab) was finally approved in the US on 27 October after one and a half years of twists and turns under review.

  • The partners are stepping up joint and/or separate efforts to develop Loqtorzi in combination with other novel agents in the US

Loqtorzi went through twists and turns for its biologics license application with the US Food and Drug

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