MindMed Ready To Take LSD Therapy Into Phase III For Anxiety

Treatment Infrastructure In Place Due To J&J’s Spravato

Mind Medicine’s LSD product MM120 will move into Phase III in the second half of 2024 after it showed efficacy in generalized anxiety disorder out to 12 weeks with a single administration in Phase IIb. 

Depression and anxiety concept of woman in fetal position on the sofa with gloomy colors
Half of anxiety patients seeking treatment do not respond to first-line drugs • Source: Shutterstock

Mind Medicine, Inc. (MindMed) plans to take MM120 (lysergide D-tartrate), a proprietary low-dose formulation of the psychedelic drug LSD, into Phase III clinical trials in generalized anxiety disorder (GAD) during the second half of 2024 based on continued positive data readouts from a Phase IIb trial, including a 7 March update that showed a single dose of the drug effectively treated GAD for up to 12 weeks after administration.

Key Takeaways
  • MindMed reported updated Phase IIb results for LSD derivative MM120 that showed a single treatment for generalized anxiety worked for up to 12 weeks.

  • The company raised $175m to support its planned Phase III program, which it expects to initiate in the second half of 2024

New York-headquartered MindMed rose 52.9% to close at $9.08 per share based on the Phase IIb trial update. The company wasted no time in raising money in tandem with the news, grossing $175m from a follow-on public offering of 16.7 million shares and a concurrent private placement of 12

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